This article discusses a case series examining the use of individualized homeopathic treatments for Non-Alcoholic Fatty Liver Disease (NAFLD), a common liver disorder characterized by excessive hepatic lipid accumulation, often linked to obesity and diabetes. Liver fibrosis, a major health concern affecting nearly 100 million people globally, contributes to significant morbidity and mortality as a consequence of chronic liver diseases, characterized by collagen and extracellular matrix accumulation due to ongoing liver injury. Clinical and experimental studies indicate that oxidative stress (OS) plays a critical role in fibrosis progression, with OS-related molecules functioning as key mediators influencing molecular and cellular mechanisms that drive liver fibrosis.