The toxin of the Primrose occurs in the glandular hair that breaks easily and releases an irritating fluid that is absorbed by the skin. The signs of poisoning appears in the sensitive patients even without direct contact with the plant . The remedy treats pain in the liver and spleen, weakness, paralysis, blisters, deep infiltration and tension of the tissues and soreness in the pharynx with decrease in the facial irritation. Face - Treats boils and eruptions on the chin, swelling of the eyelids which burn at night, skin rashes and eczema. Skin - The remedy covers itching which worsens at night, small eruptions on a raised base, red and swollen. Infections and skin symptoms with feverish symptoms. Extremities -  As reported, it cures eczema on arms, hands, fingers, forearms with pain around the shoulder. Purple blotches at the back of hands, dry and hot palms, cracking, stiffness and blisters on the fingers.